KIDNEY STONES NEWS FROM ACROSS THE INTERNET UPDATED
29 Jul 2010 at 11:54pm
by Urological Research
23 Jul 2010 at 11:00am
Abstract A simple method for preparing artificial kidney stones with varying physical properties is described. BegoStone was prepared
with a powder-to-water ratio ranging from 15:3 to 15:6. The acoustic properties of the phantoms were characterized using an
ultrasound transmission technique, from which the corresponding mechanical properties were calculated based on elastic wave
theory. The measured parameters for BegoStone phantoms of different water contents are: longitudinal wave speed (3,148–4,159 m/s),
transverse wave speed (1,813–2,319 m/s), density (1,563–1,995 kg/m3), longitudinal acoustic impedance (4.92–8.30 kg/m2 s), transverse acoustic impedance (2.83–4.63 kg/m2 s), Young’s modulus (12.9–27.4 GPa), bulk modulus (8….
by Urological Research
21 Jul 2010 at 10:00pm
Authors: Esch E, Simmons WN, Sankin G, Cocks HF, Preminger GM, Zhong P
A simple method for preparing artificial kidney stones with varying physical properties is described. BegoStone was prepared with a powder-to-water ratio ranging from 15:3 to 15:6. The acoustic properties of the phantoms were characterized using an ultrasound transmission technique, from which the corresponding mechanical properties were calculated based on elastic wave theory. The measured parameters for BegoStone phantoms of different water contents are: longitudinal wave speed (3,148-4,159 m/s), transverse wave speed (1,813-2,319 m/s), density (1,563-1,995 kg/m(3)), longitudinal acoustic impedance (4.92-8.30 kg/m(2) s), transverse acoustic impedance (2.83-4.63 kg/m(2) s), Young’s modulus (12.9-27.4 GPa), bulk mod…
by Health News from Medical News Today
21 Jul 2010 at 8:00am
Mark Mulac was an “avid lover” of iced tea, downing up to six glasses a day of the popular summertime thirst-quencher. “I was a junkie on a bender. I had to have it every day,” said Mulac, a resident of Brookfield, Ill. “Iced tea was very refreshing, cheap to buy and easy to make.” Unfortunately, for health reasons, Mulac has been forced to go cold turkey. All the iced tea he was downing helped to bring on an excruciating bout of kidney stones that eventually led to surgery at Loyola University Hospital in Maywood, Ill… (Source: Health News from Medical News Today)
by Urological Research
16 Jul 2010 at 3:47pm
Abstract Patients who form calcium kidney stones often have metabolic disorders such as idiopathic hypercalciuria (IH) that reflect
abnormalities in mineral handling in the kidney. Renal handling of calcium is altered by ingestion of nutrients such as carbohydrates,
protein, and sodium, and patients with IH appear to be more sensitive to these stimuli. Studies using probes such as diuretics
or lithium clearance have the ability to clarify which nephron segments are involved in the altered renal calcium transport
with nutrient seen in IH. Studies in the genetic hypercalciuric rat demonstrate alterations in both proximal tubule and thick
ascending limb calcium reabsorption. Similar studies in humans have begun to provide evidence about the corresponding abnormalities
in ston…
by Urological Research
14 Jul 2010 at 10:00pm
Authors: Worcester EM, Coe FL
Patients who form calcium kidney stones often have metabolic disorders such as idiopathic hypercalciuria (IH) that reflect abnormalities in mineral handling in the kidney. Renal handling of calcium is altered by ingestion of nutrients such as carbohydrates, protein, and sodium, and patients with IH appear to be more sensitive to these stimuli. Studies using probes such as diuretics or lithium clearance have the ability to clarify which nephron segments are involved in the altered renal calcium transport with nutrient seen in IH. Studies in the genetic hypercalciuric rat demonstrate alterations in both proximal tubule and thick ascending limb calcium reabsorption. Similar studies in humans have begun to provide evidence about the corresponding abnormalities…
MedWorm Message: Register for MedMatcha, MedWorm’s medical advertising network, and receive $5 free advertising.
by Johns Hopkins Medicine News
14 Jul 2010 at 5:44am
Obesity in general nearly doubles the risk of developing kidney stones, but the degree of obesity doesn’t appear to increase or decrease the risk one way or the other, a new study from Johns Hopkins shows. (Source: Johns Hopkins Medicine News)
by Urological Research
13 Jul 2010 at 1:46pm
Abstract The mechanisms involved in biomineralization are modulated through interactions with organic matrix. In the case of stone
formation, the role of the organic macromolecules in the complex urinary environment is not clear, but the presence of mineralogical
‘signatures’ suggests that some aspects of stone formation may result from a non-classical crystallization process that is
induced by acidic proteins. An amorphous precursor has been detected in many biologically controlled mineralization reactions,
which is thought to be regulated by non-specific interactions between soluble acidic proteins and mineral ions. Using in vitro
model systems, we find that a liquid-phase amorphous mineral precursor induced by acidic polypeptides can lead to crystal
textures that re…
by Urological Research
12 Jul 2010 at 10:00pm
Authors: Gower LB, Amos FF, Khan SR
The mechanisms involved in biomineralization are modulated through interactions with organic matrix. In the case of stone formation, the role of the organic macromolecules in the complex urinary environment is not clear, but the presence of mineralogical ’signatures’ suggests that some aspects of stone formation may result from a non-classical crystallization process that is induced by acidic proteins. An amorphous precursor has been detected in many biologically controlled mineralization reactions, which is thought to be regulated by non-specific interactions between soluble acidic proteins and mineral ions. Using in vitro model systems, we find that a liquid-phase amorphous mineral precursor induced by acidic polypeptides can lead to crystal textur…
by Molecular Cytogenetics
8 Jul 2010 at 10:00pm
Conclusions:
We report on an adult patient with multiple congenital abnormalities who had in 13% of his cells a unique supernumerary ring chromosome 18 that was composed of 6 copies of the 5 Mb gene rich region of 18q11. (Source: Molecular Cytogenetics)
by Am J Physiol Renal P…
6 Jul 2010 at 10:00pm
Authors: Pajor AM, Sun NN
The sodium-coupled transport of citric acid cycle intermediates in the intestine and kidney is mediated by the Na+/dicarboxylate cotransporter, NaDC1. In the kidney, NaDC1 plays an important role in regulating succinate and citrate concentrations in the urine, which may have physiological consequences including the development of kidney stones. In the present study, the impact of non-synonymous single nucleotide polymorphisms (SNPs) on NaDC1 expression and function was characterized using the COS-7 cell heterologous expression system. The I550V variant had an increased sensitivity to lithium inhibition although there were no significant effects on protein abundance. The L44F variant had no significant effects on expression or function. The membrane protein abu…
MedWorm Message: Register for MedMatcha, MedWorm’s medical advertising network, and receive $5 free advertising.
by Journal of Biological Chemistry
2 Jul 2010 at 12:37pm
Calcium oxalate stone formation occurs under pathological conditions and accounts for more than 80% of all types of kidney stones. In the current study, we show for the first time that calcium oxalate stones are formed in the mouse inner ear of a genetic model for hearing loss and vestibular dysfunction in humans. The vestibular system within the inner ear is dependent on extracellular tiny calcium carbonate minerals for proper function. Thousands of these biominerals, known as otoconia, are associated with the utricle and saccule sensory maculae and are vital for mechanical stimulation of the sensory hair cells. We show that a missense mutation within the Slc26a4 gene abolishes the transport activity of its encoded protein, pendrin. As a consequence, dramatic changes in mineral compositio…
by Urology
30 Jun 2010 at 10:00pm
This is a well-written article that presents convincing data on increased risk for kidney stones in the pediatric age group when patients have low 24-hour urine citrate, high 24-hour urinary calcium/creatinine ratio, or both. Similar data have been published many times on adults, but there are fewer studies demonstrating this in children. Normal values were admittedly difficult to obtain for some urine chemistry parameters, and the authors indicate this in their study and describe ways to obtain such norms from the published literature. Cystine stones were excluded from this study. (Source: Urology)
by JEMS: Journal of Emergency Medical Services
30 Jun 2010 at 10:00pm
Anyone who flies regularly along the front range of Colorado quickly learns to adapt to the turbulent nature of the altitude gods who love to fling unwary souls within the confines of a compressed, metallic cylinder traveling at speeds eight times faster than you can drive an ex-lax overdose code 3 to the hospital. Inevitably, despite the pilot’s hopeless attempt to find thin pockets of smooth air for the 30-minute voyage, kidney stones will be jolted free, and the sounds of eustachian tubes imploding are heard throughout the passenger cabin. (Source: JEMS: Journal of Emergency Medical Services)
by Nephrology Dialysis Transplantation
24 Jun 2010 at 8:33pm
Conclusion. SNPs and CATTCA haplotype of the CaSR gene first block is associated with kidney stones in normocitraturic patients. (Source: Nephrology Dialysis Transplantation)
by Pediatric Nephrology
20 Jun 2010 at 10:28pm
Abstract Nephrolithiasis is a cause of significant morbidity and medical care expenses worldwide. Its prevalence has increased steadily
during the last three decades among both adults and children. This trend suggests that changing environmental factors play
a significant role in the risk of developing kidney stones although, conversely, there are many indications that genes play
an important role in this condition as well. A limited number of monogenic forms have been identified, but the majority of
nephrolithiasis cases are the result of complex, multi-factorial interactions between genetic inheritance and environmental
exposure. Scientific evidence indicates that inheritance accounts for about half of the risk of common forms, making these
forms suitable for investigati…
MedWorm Message: Register for MedMatcha, MedWorm’s medical advertising network, and receive $5 free advertising.
by BMC Family Practice
20 Jun 2010 at 10:00pm
Conclusions These new algorithms have the potential to identify high risk patients who might benefit from more detailed assessment, closer monitoring or interventions to reduce their risk. (Source: BMC Family Practice)
by Health News from Medical News Today
15 Jun 2010 at 9:00am
Scientists from the University of Leeds have discovered the mechanisms of a protein known to play an active part in the inherited kidney disorder, Dent’s disease. The findings provide a new focus for future therapies for the disease, for which there is currently no cure. Dent’s disease is an extremely rare illness caused by a genetic mutation on the X chromosome. Affecting mostly men, its main symptom is kidney stones often followed by a deterioration of kidney function and in many cases chronic kidney failure… (Source: Health News from Medical News Today)
by Medscape Diabetes Headlines
11 Jun 2010 at 7:00pm
Along with their well-known risk for uric acid nephrolithiasis, diabetics seem to be at higher risk for calcium oxalate stones, according to a new study. Reuters Health Information (Source: Medscape Diabetes Headlines)
by American Journal of Physiology. Renal Physiology
8 Jun 2010 at 10:00pm
Authors: Li Y, McLaren MC, McMartin KE
Ethylene glycol (EG) exposure is a common model for kidney stones, because animals accumulate calcium oxalate monohydrate (COM) in kidneys. Wistar rats are more sensitive to EG than F344 rats, with greater COM deposition in kidneys. The mechanisms by which COM accumulates differently among strains are poorly understood. Urinary proteins inhibit COM adhesion to renal cells, which could alter COM deposition in kidneys. We hypothesize that COM accumulates more in Wistar rat kidneys because of lower levels of inhibitory proteins in urine. Wistar and F344 rats were treated with 0.75% EG in drinking water for 8 wk. 24-h urine was collected every 2 wk for analysis of urinary proteins. Similar studies were conducted for 2 wk using 2% hydroxyproline (HP) a…
by MedlinePlus Health News
1 Jun 2010 at 12:00pm
Here’s how you can help relieve symptoms
Source: HealthDay
Related MedlinePlus Page: Kidney Stones (Source: MedlinePlus Health News)
MedWorm Message: Register for MedMatcha, MedWorm’s medical advertising network, and receive $5 free advertising.
by NaturalNews.com
18 May 2010 at 6:00am
(NaturalNews) The “most retarded science journal of the year” award goes to the Journal of Urology which has published an article suggesting that diet soda is actually an effective type of medicine for preventing kidney stones (April 19, 2010 issue). The research was led by Dr Brian H. Eisner, a urologist at Massachusetts General Hospital in Boston, who is apparently completely clueless about human nutrition and the toxicity of aspartame.According to Dr Eisner, diet sodas are not only good medicine for preventing kidney stones; they’re also a good source of water hydration. Noting that patients need to consume 2-3 liters of water each day, Dr Eisner said in a Reuters article, “If drinking these sodas helps people reach that goal, then that may be a good thing.” (http://www.reuters.com/arti…
by the Mail online | Health
17 May 2010 at 12:42pm
An ingredient in low calories citrus drinks could help prevent people from developing kidney stones. Researchers found that the diet versions of softdrinks such as 7Up, Sunkist and Sprite contained relatively high amounts of a compound called citrate. (Source: the Mail online | Health)
by Arquivos Brasileiros de Endocrinologia e Metabologia
16 May 2010 at 12:08pm
Primary hyperparathyroidism is a common disorder of mineral metabolism characterized by incompletely regulated, excessive secretion of parathyroid hormone from one or more of the parathyroid glands. The historical view of this disease describes two distinct entities marked by two eras. When primary hyperparathyroidism was first discovered about 80 years ago, it was always symptomatic with kidney stones, bone disease and marked hypercalcemia. With the advent of the multichannel autoanalyzer about 40 years ago, the clinical phenotype changed to a disorder characterized by mild hypercalcemia and the absence of classical other features of the disease. We may now be entering a 3rd era in the history of this disease in which patients are being discovered with normal total and ionized serum calci…
MedWorm Message: Register for MedMatcha, MedWorm’s medical advertising network, and receive $5 free advertising.
by Sound Medicine
15 May 2010 at 10:00pm
Did you know that drinking lemonade can help prevent kidney stones?
Anyone who’s had a kidney stone knows that trying to get rid of it can be one of life’s more uncomfortable experiences, to put it mildly.
So if you’re prone to having kidney stones, it’s wise to do what you can to prevent them.
And lemonade, or just lemon juice, turns out to be one of the better ways.
Why?
Because l…. (Source: Sound Medicine)
|
photo credit: bradleypjohnson
